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Invitrogen™ FLIP Monoclonal Antibody (7A3D12)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA531679
Description
MA5-31679 has been tested in indirect ELISA.
FLIP (CFLAR) is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells. It acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.
Specifications
FLIP | |
Monoclonal | |
1 mg/mL | |
PBS with 0.05% sodium azide | |
O15519, O35732 | |
CFLAR | |
Purified recombinant fragment of human CFLAR (AA: 100-251) expressed in E. coli. | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG1 |
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot | |
7A3D12 | |
Unconjugated | |
CFLAR | |
2310024N18Rik; A430105C05Rik; Cash; CASP8 and FADD like apoptosis regulator; CASP8 and FADD-like apoptosis regulator; CASP8 and FADD-like apoptosis regulator subunit p12; CASP8 and FADD-like apoptosis regulator subunit p43; CASP8AP1; caspase homolog; Caspase-eight-related protein; caspase-like apoptosis regulatory protein; caspase-related inducer of apoptosis; Casper; Cellular FLICE-like inhibitory protein; Cflar; c-Flip; c-FLIPL; c-FLIPR; c-FLIPS; CLARP; ENSMUSG00000072980; FADD-like antiapoptotic molecule 1; FLAME; FLAME1; FLAME-1; Flip; Gm9845; I-FLICE; Inhibitor of FLICE; MACH-related inducer of toxicity; MRIT; testis secretory sperm-binding protein Li 233m; usurpin; usurpin beta | |
Mouse | |
Protein G | |
RUO | |
12633, 8837 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
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