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FLNC Rabbit, anti-Human, Unconjugated, Polyclonal, Proteintech
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Description
Filamin C (FLNC; also known as γ-FLN; ABP-L; FLN2), a muscle-specific filamin and a large actin-cross-linking protein. Human filamins are ∼280 kDa homodimers, each monomer consisting of an N-terminal actin-binding domain followed by 24 immunoglobulin (Ig)-like domains (d1 to d24), the last of which mediates dimerization. FLNC is specifically expressed in cardiomyocytes and skeletal myocytes and is involved in the maintenance of structural integrity. High filamin C associated with better prognosis of prostate cancer, leukemia and breast cancer patients. ( PMID: 25577646, PMID: 30867563, PMID: 31131323)
Specifications
Specifications
| Antigen | FLNC |
| Applications | Western Blot, ELISA |
| Classification | Polyclonal |
| Concentration | 300 μg/mL |
| Conjugate | Unconjugated |
| Host Species | Rabbit |
| Quantity | 150 μL |
| Primary or Secondary | Primary |
| Gene ID (Entrez) | 2318 |
| Target Species | Human |
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