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Invitrogen™ FLT3 (CD135) Polyclonal Antibody
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Catalog No. PIPA579270
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100 μg
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Catalog No. Quantity
PIPA579270 100 μg
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Catalog No. PIPA579270 Supplier Invitrogen™ Supplier No. PA579270
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: mouse brain tissue. IHC: mouse small intestine tissue, rat kidney tissue, rat liver tissue, rat small intestine tissue, mouse kidney tissue.

FLT3 is a tyrosine protein kinase that is a member of the growth factor receptor tyrosine kinase family. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FLT3 (CD135)
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose, 0.9mg NaCl, 0.2mg Na2PO4 and no preservative
Gene FLT3
Gene Accession No. Q00342
Gene Alias B230315G04; CD135; CD135 antigen; fetal liver kinase 2; Fetal liver kinase-2; FL cytokine receptor; FLK2; Flk-2; FLT3; Flt-3; fms related tyrosine kinase 3; FMS-like tyrosine kinase 3; fms-related tyrosine kinase 3; growth factor receptor tyrosine kinase type III; Ly72; OTTHUMP00000214829; Receptor-type tyrosine-protein kinase FLT3; RP11-153M24.3; stem cell tyrosine kinase 1; STK1; STK-1; tyrosine-protein kinase FLT3; tyrosine-protein kinase receptor flk-2; wmfl
Gene Symbols FLT3
Host Species Rabbit
Immunogen E. coli-derived mouse Flt3 / CD135 recombinant protein (Position: E62-E295).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 140635, 14255
Target Species Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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