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FLT4 Mouse anti-Human, Clone: OTI9G6, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF806910

Encompass_Preferred

Catalog No. 50-166-8035


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Vascular endothelial growth factor is a key regulator of blood vessel development in embryos and angiogenesis in adult tissues. Unlike VEGF, the related VEGFC stimulates the growth of lymphatic vessels through its specificl ymphatic endothelial receptor VEGFR-3. In 1998, Dumont showed that targeted inactivation of the VEGFR-3 gene in mice resulted in defective blood vessel development in early embryos. Vasculogenesis and angiogenesis occurred, but large vessels became abnormally organized with defective lumens, leading to fluid accumulation in the pericardial cavity and cardiovascular failure at embryonic day 9.5. Thus, VEGFR3 has an essential role in the development of theembryonic cardiovascular system before the emergence of the lymphatic vessels.
Specifications

Specifications

FLT4
Monoclonal
Unconjugated
FLT4
FLT-4, FLT41, LMPH1A, PCL, VEGFR-3, VEGFR3
Mouse
Affinity Chromatography
RUO
2324
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Western Blot
OTI9G6
PBS with 8% trehalose and no preservative; pH 7.3
P35916
FLT4
Human recombit protein fragment corresponding to amino acids 1063-1363 of human FLT4 produced in E.coli.
100 μg
Primary
Human
Antibody
IgG1
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