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  5. Tocris Bioscience™ Fludarabine

Tocris Bioscience™ Fludarabine
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Catalog No. 349550
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Purine analog; inhibits DNA synthesis

Purine analog that inhibits DNA synthesis. Exhibits antiproliferative activity (IC50 = 1.54 μM in RPMI cells) and triggers apoptosis through increasing Bax and decreasing Bid, XIAP and survivin expression. Inhibits cytokine-induced activation of STAT1 and STAT1-dependent gene transcription in lymphocytes. Also displays anticancer activity against hematological malignancies in vivo.

Chemical Identifiers

CAS 21679-14-1
Molecular Formula C10H12FN5O4

Specifications

Quantity 50 mg
Formula Weight 285.23
Purity >99%
Molecular Weight (g/mol) 285.24
Chemical Name or Material Fludarabine

Safety and Handling

Recommended Storage Desiccate at +4°C
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