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  5. Tocris Bioscience™ Fluticasone propionate

Tocris Bioscience™ Fluticasone propionate
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Catalog No. 200750 Shop All Novus Biologicals Products
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Catalog No. Quantity
20-075-0 50 mg
20-071-0 10 mg
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Catalog No. 20-075-0 Supplier Tocris Bioscience™ Supplier No. 2007/50
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Description

Selective high affinity glucocorticoid receptor agonist

High affinity, selective glucocorticoid receptor agonist (Kd = 0.5 nM). Potently stimulates glucocorticoid receptor-mediated transactivation of gene expression and enhances human eosinophil apoptosis (EC50 = 3.7 nM) in vitro. Inhibits mast cell accumulation in nasal mucosa following topical administration. Lipophilic anti-inflammatory agent with low oral bioavailability. Also potentiates KV1 channels (EC50 = 37 nM).

Chemical Identifiers

CAS 80474-14-2
Molecular Formula C25H31F3O5S

Specifications

Quantity 50 mg
Formula Weight 500.57
Purity >98%
Molecular Weight (g/mol) 505.604
Chemical Name or Material Fluticasone propionate

Safety and Handling

Recommended Storage Store at Room Temperature
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