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Tocris Bioscience™ FMF-04-159-R
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Catalog No. 715910
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Catalog No. Quantity
71-591-0 10 mg
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Catalog No. 71-591-0 Supplier Tocris Bioscience™ Supplier No. 7159/10
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Description

Potent CDK14 and CDK16 inhibitor; displays reversible inhibition of CDK14

FMF-04-159-R is a potent inhibitor of CDK16 and CDK14 (IC50 values are 6 and 140 nM, respectively in kinase activity assay; IC50 = 563 nM for CDK14 in BRET assay). Also binds CDK2 (IC50 = 493 nM). Inhibition reversible upon compound wash-out. Control for FMF-04-159-2 (Cat. No. 7158).

Specifications

Chemical Name or Material N-(1-((3-(4-(Dimethylamino)butanamido)phenyl)sulfonyl)piperidin-4-yl)-4-(2,4,6-trichlorobenzamido)-1 H-pyrazole-3-carboxamide
Quantity 10 mg
Target Cyclin-dependent Kinase Inhibitors
Molecular Formula C28H32Cl3N7O5S
Purity 0.98
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