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Tocris Bioscience Fmk
Irreversible ribosomal S6 kinase 1/2 inhibitor
Manufacturer: Tocris Bioscience 4690/10
This item is not returnable.
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Description
- IC50 = 15 nM
- Inactivates the C-terminal auto-kinase domain activity
- Suppresses RSK2 kinase activity in RSK2-expressing HNSCC cell lines
- Reduces HNSCC cell invasive ability
- Displays no effect on EGF-stimulated phosphorylation of ERK1 or ERK2
Specifications
1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone | |
C18H19FN4O2 | |
10 mg |
821794-92-7 | |
342.37 | |
0.97 |
Safety and Handling
Recommended Storage : Store at -20°C
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