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Tocris Bioscience™ Fmk

Irreversible ribosomal S6 kinase 1/2 inhibitor

Manufacturer:  Tocris Bioscience™ 4690/10

Catalog No. 46-901-0


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Description

Description

  • IC50 = 15 nM
  • Inactivates the C-terminal auto-kinase domain activity
  • Suppresses RSK2 kinase activity in RSK2-expressing HNSCC cell lines
  • Reduces HNSCC cell invasive ability
  • Displays no effect on EGF-stimulated phosphorylation of ERK1 or ERK2
Specifications

Specifications

1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone
821794-92-7
342.37
0.97
C18H19FN4O2
10 mg
Safety and Handling

Safety and Handling

Recommended Storage : Store at -20°C

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