Invitrogen™ FMN2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA565632

Catalog No. PIPA565632

Description

Immunogen sequence: GVASDSGGGVS PALAAKASGA PAAADGFQNV FTGRTLLEKL FSQQENGPPE EAEKFCSRII AMGLLLPFSD CFREPCNQNA QTNAASFDQD QLYTWAAVSQ PTHSLDYSEG Highest antigen sequence identity to the following orthologs - mouse 86%, rat 86%.

FMN2, a novel formin homology protein of the cappuccino subfamily, is highly conserved between evolutionarily diverse vertebrates. FMN2 bears a high degree of similarity to formin-1 which is the founding member of formin homology proteins. FMN2 plays a crucial role in maintenance of the meiotic spindle. The protein is widely expressed in human fetal brain, adult whole brain, hypothalamus, retina, pancreatic islet and germinal-center B cells. Pathological role of the protein is identified in various tumors like parathyloid tumor, glioblastoma, retinoblastoma and chondrosarcoma. FMN2 mutations are often a cause of unexplained infertility in women. The gene encoding for human FMN2 is localized in the chromosomal region 1q43.

Specifications

• Antigen: FMN2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FMN2
• Gene Alias: AU024104; FMN2; formin 2; formin-2; RP11-90L13.1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56776
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.20 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9NZ56
• Gene Symbols: FMN2
• Immunogen: Recombinant Human FMN2. Recombinant protein control fragment (Product #RP-106300).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov