Invitrogen™ FMO2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA522068

Catalog No. PIPA522068

Description

Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji. Predicted reactivity: Mouse (83%), Rat (82%), Rabbit (84%), Rhesus Monkey (96%), Chimpanzee (99%), Bovine (81%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in humans, this enzyme is truncated and is probably rapidly degraded. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1.

Specifications

• Antigen: FMO2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Fmo2
• Gene Alias: 2310008D08Rik; 2310042I22Rik; AW107733; Dimethylaniline monooxygenase [N-oxide-forming] 2; dimethylaniline oxidase 2; flavin containing dimethylaniline monoxygenase 2; flavin containing monooxygenase 2; flavin containing monooxygenase 2 (non-functional); FMO 1B1; FMO 2; FMO, pulmonary; FMO1B1; FMO2; Pulmonary flavin-containing monooxygenase 2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2327
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q99518
• Gene Symbols: Fmo2
• Immunogen: Recombinant fragment corresponding to a region within amino acids 74 and 354 of FMO2 (Uniprot ID#Q99518).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov