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Invitrogen™ FMO2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA522068
Description
Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji. Predicted reactivity: Mouse (83%), Rat (82%), Rabbit (84%), Rhesus Monkey (96%), Chimpanzee (99%), Bovine (81%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in humans, this enzyme is truncated and is probably rapidly degraded. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1.
Specifications
FMO2 | |
Polyclonal | |
Unconjugated | |
Fmo2 | |
2310008D08Rik; 2310042I22Rik; AW107733; Dimethylaniline monooxygenase [N-oxide-forming] 2; dimethylaniline oxidase 2; flavin containing dimethylaniline monoxygenase 2; flavin containing monooxygenase 2; flavin containing monooxygenase 2 (non-functional); FMO 1B1; FMO 2; FMO, pulmonary; FMO1B1; FMO2; Pulmonary flavin-containing monooxygenase 2 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
2327 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
1 mg/mL | |
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 | |
Q99518 | |
Fmo2 | |
Recombinant fragment corresponding to a region within amino acids 74 and 354 of FMO2 (Uniprot ID#Q99518). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
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