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Invitrogen™ FMO2 Polyclonal Antibody
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Catalog No. PIPA5109732
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100 μL
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PIPA5109732 100 μL
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Catalog No. PIPA5109732 Supplier Invitrogen™ Supplier No. PA5109732
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VFISTRHGTW VMSRISEDGY PWDSVFHTRF RSMLRNVLPR TAVKWMIEQQ MNRWFNHENY GLEPQNKYIM KEPVLNDDVP SRLLCGAIKV KSTVKELTET SAIFEDGTVE ENIDVIIFAT GYSFSFPFLE DSLVKVENNM VSLYKYIFPA HLDKSTLACI GLIQPLGSIF PTAELQARWV TRVFKGLCSL PSERTMMMDI IKRNEKRIDL FGESQSQTLQ TNYVDYLDEL ALEIGAKPDF CSLLFKDPKL AVRLYFGPCN S.

The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in humans, this enzyme is truncated and is probably rapidly degraded. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FMO2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.66 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Fmo2
Gene Accession No. Q99518
Gene Alias 2310008D08Rik; 2310042I22Rik; AW107733; Dimethylaniline monooxygenase [N-oxide-forming] 2; dimethylaniline oxidase 2; flavin containing dimethylaniline monoxygenase 2; flavin containing monooxygenase 2; flavin containing monooxygenase 2 (non-functional); FMO 1B1; FMO 2; FMO, pulmonary; FMO1B1; FMO2; Pulmonary flavin-containing monooxygenase 2
Gene Symbols Fmo2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 210-470 of human FMO2 (NP_001451.2).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2327
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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