Invitrogen™ FMO3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529807

Catalog No. PIPA529807

Description

Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse liver. Predicted reactivity: Mouse (80%), Rat (81%), Dog (84%), Rabbit (81%), Rhesus Monkey (93%), Chimpanzee (100%), Bovine (83%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The mammalian flavin-containing monooxygenases (FMO; EC 1.14.13.8) represent a multigene family whose gene products are localized in the endoplasmic reticulum of many tissues. These enzymes catalyze the NADPH-dependent oxidative metabolism of many drugs, pesticides, and other foreign compounds. Their substrates are soft nucleophiles with an electron-rich center, typically a nitrogen, sulfur or phosphorus-containing functional group, as the site for oxidative attack by the enzyme.

Specifications

• Antigen: FMO3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Fmo3
• Gene Alias: AW111792; Dimethylaniline monooxygenase [N-oxide-forming] 3; dimethylaniline oxidase 3; dJ127D3.1; flavin containing dimethylaniline monoxygenase 3; flavin containing monooxygenase 3; flavin-containing monooxygenase 3; flavin-containing monooxygenase FMO3; FM03; FMO 1D1; FMO 3; FMO form 2; FMO II; FMO3; FMOII; hepatic flavin-containing monooxygenase 3; hepatic flavin-containing monooxygenase-3; MGC34400; TMAU; Trimethylamine monooxygenase; Unknown (protein for MGC:128044)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14262, 2328
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.91 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P31513, P97501
• Gene Symbols: Fmo3
• Immunogen: Recombinant protein encompassing a sequence within the center region of human FMO3. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov