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Invitrogen™ FMO5 Polyclonal Antibody
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Catalog No. PIPA552932
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100 μL
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PIPA552932 100 μL
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Catalog No. PIPA552932 Supplier Invitrogen™ Supplier No. PA552932
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PLGAIMPISE LQGRWATQVF KGLKTLPSQS EMMAEISKAQ EEIDKRYVES QRHTIQGDYI DTMEELADLV GVRPNLLSLA FTDPKLALHL LLGPCTPIHY RVQGPGKWDG ARKAILTTDD Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 86%.

Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FMO5
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene FMO5
Gene Accession No. P49326
Gene Alias 5033418D19Rik; AI195026; Dimethylaniline monooxygenase [N-oxide-forming] 5; dimethylaniline oxidase 5; flavin containing monooxygenase 5; FMO 5; Fmo5; Hepatic flavin-containing monooxygenase 5
Gene Symbols FMO5
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human FMO5. Recombinant protein control fragment (Product #RP-90221).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2330
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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