FMR1 Mouse anti-Canine, Human, Mouse, Rat, Clone: OTI2C3, lyophilized, TrueMAB™

Catalog No.	Quantity
50-166-2781	100 μg

Catalog No. 50-166-2781 Supplier OriGene Supplier No. CF504293

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

FMR1 binds RNA and is associated with polysomes. The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat in the 5′ UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure. Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

Specifications

• Antigen: FMR1
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI2C3
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: FMR1
• Gene Accession No.: P35922, Q06787, Q80WE1
• Gene Alias: FMRP, FRAXA, POF, POF1
• Gene Symbols: FMR1
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 26-279 of human FMR1 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 14265, 2332, 24948, 481070
• Target Species: Canine, Human, Mouse, Rat
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG2a