FMR1 Mouse anti-Canine, Human, Mouse, Rat, Clone: OTI2C3, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF504293

Catalog No. 50-166-2781

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

FMR1 binds RNA and is associated with polysomes. The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat in the 5′ UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure. Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

Specifications

• Antigen: FMR1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: FMR1
• Gene Alias: FMRP, FRAXA, POF, POF1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14265, 2332, 24948, 481070
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI2C3
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P35922, Q06787, Q80WE1
• Gene Symbols: FMR1
• Immunogen: Human recombit protein fragment corresponding to amino acids 26-279 of human FMR1 produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Canine, Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2a