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FNBP3 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501982691
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50-198-2691 100 μL
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Catalog No. 50-198-2691 Supplier Bioss Supplier No. BS13190R
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Description

Rabbit Polyclonal Antibody

FNBP3, Formin-binding protein 3, is a 957 amino acid protein encoded by the human gene PRPF40A. FNBP3 belongs to the PRPF40 family and contains five FF domains and two WW domains. Nuclear proteins harboring both WW and FF protein interaction modules bind to splicing factors as well as RNA polymerase II and may serve to link transcription with splicing. Through the WW domains, FNBP3 will bind to the Formin proline-rich regions. Also known as Pre-mRNA-processing factor 40 homolog A, FNBP3 binds to WASL/N-WASP (Neuronal Wiskott-Aldrich syndrome protein) complex and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function. FNBP3 is widely expressed in most tissues and is localized to the nuclear speckles.

Specifications

Antigen FNBP3
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene PRPF40A
Gene Accession No. O75400
Gene Alias 2810012K09Rik; Fas ligand-associated factor 1; Fas-ligand associated factor 1; FBP11; FBP-11; FLAF1; FLJ20585; Fnbp11; Fnbp3; formin binding protein 11; formin binding protein 3; Formin-binding protein 11; Formin-binding protein 3; HIP10; HIP-10; HSPC225; Huntingtin yeast partner A; Huntingtin-interacting protein 10; Huntingtin-interacting protein A; HYPA; NY-REN-6; NY-REN-6 antigen; pre-mRNA processing factor 40 homolog A; Pre-mRNA-processing factor 40 homolog A; Prp40; PRP40 pre-mRNA processing factor 40 homolog A; PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae); PRP40 pre-mRNA processing factor 40 homolog A (yeast); Prpf40a; Renal carcinoma antigen NY-REN-6
Gene Symbols PRPF40A
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human FNBP3.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55660
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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