Invitrogen™ FNIP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA564359

Catalog No. PIPA564359

Description

Immunogen sequence: HHTKPLKEER GAIDQHQETK QTTKDQSGES DTQNMVSEEP CELPCWNHSD PESMSLFDEY FNDDSIETRT IDDVPF Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 79%.

FNIP1 encodes a protein that binds to the tumor suppressor protein folliculin and to AMP-activated protein kinase (AMPK). The encoded protein participates in the regulation of cellular metabolism and nutrient sensing by modulating the AMPK and target of rapamycin signaling pathways. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin. Diseases associated with FNIP1 include Birt-Hogg-Dube Syndrome and Pleural Disease.

Specifications

• Antigen: FNIP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FNIP1
• Gene Alias: A730024A03Rik; AI838773; AW557298; FNIP1; folliculin interacting protein 1; folliculin-interacting protein 1; Kiaa1961
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 96459
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8TF40
• Gene Symbols: FNIP1
• Immunogen: Recombinant protein corresponding to Human FNIP1. Recombinant protein control fragment (Product #RP-104226).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG