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Invitrogen™ FNIP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA564359

Catalog No. PIPA564359


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Description

Description

Immunogen sequence: HHTKPLKEER GAIDQHQETK QTTKDQSGES DTQNMVSEEP CELPCWNHSD PESMSLFDEY FNDDSIETRT IDDVPF Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 79%.

FNIP1 encodes a protein that binds to the tumor suppressor protein folliculin and to AMP-activated protein kinase (AMPK). The encoded protein participates in the regulation of cellular metabolism and nutrient sensing by modulating the AMPK and target of rapamycin signaling pathways. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin. Diseases associated with FNIP1 include Birt-Hogg-Dube Syndrome and Pleural Disease.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

FNIP1
Polyclonal
Unconjugated
FNIP1
A730024A03Rik; AI838773; AW557298; FNIP1; folliculin interacting protein 1; folliculin-interacting protein 1; Kiaa1961
Rabbit
Antigen Affinity Chromatography
RUO
96459
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin)
0.1 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q8TF40
FNIP1
Recombinant protein corresponding to Human FNIP1. Recombinant protein control fragment (Product #RP-104226).
100 μL
Primary
Human
Antibody
IgG
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