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Invitrogen™ FNIP1 Polyclonal Antibody
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Catalog No. PIPA564453
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100 μL
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Catalog No. Quantity
PIPA564453 100 μL
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Catalog No. PIPA564453 Supplier Invitrogen™ Supplier No. PA564453
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DHCCMLEFSK ILCTKNNKQN NEFCKCIETV PQDSCKTCFP QQDQRDTLSI LVPHGDKESS DKKIAVGTEW D Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 82%.

FNIP1 encodes a protein that binds to the tumor suppressor protein folliculin and to AMP-activated protein kinase (AMPK). The encoded protein participates in the regulation of cellular metabolism and nutrient sensing by modulating the AMPK and target of rapamycin signaling pathways. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin. Diseases associated with FNIP1 include Birt-Hogg-Dube Syndrome and Pleural Disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FNIP1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene FNIP1
Gene Accession No. Q8TF40
Gene Alias A730024A03Rik; AI838773; AW557298; FNIP1; folliculin interacting protein 1; folliculin-interacting protein 1; Kiaa1961
Gene Symbols FNIP1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human FNIP1. Recombinant protein control fragment (Product #RP-104216).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 96459
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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