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Invitrogen™ FNIP1 Polyclonal Antibody
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Catalog No. PIPA577778
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100 μg
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Catalog No. Quantity
PIPA577778 100 μg
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Catalog No. PIPA577778 Supplier Invitrogen™ Supplier No. PA577778
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Description

Rabbit Polyclonal Antibody

A 1:1,000 dilution of PA5-77778 was sufficient for detection of FNIP1 in 15 μg of mouse kidney cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody. Detects approximately 130 kDa.

FNIP1 encodes a protein that binds to the tumor suppressor protein folliculin and to AMP-activated protein kinase (AMPK). The encoded protein participates in the regulation of cellular metabolism and nutrient sensing by modulating the AMPK and target of rapamycin signaling pathways. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin. Diseases associated with FNIP1 include Birt-Hogg-Dube Syndrome and Pleural Disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FNIP1
Applications Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene FNIP1
Gene Accession No. Q68FD7, Q8TF40
Gene Alias A730024A03Rik; AI838773; AW557298; FNIP1; folliculin interacting protein 1; folliculin-interacting protein 1; Kiaa1961
Gene Symbols FNIP1
Host Species Rabbit
Immunogen Synthetic peptide from the mid-protein of Human FNIP1 (C-ahx-SKDEDENNKFNE) (aa 339-350).
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100362347, 216742, 96459
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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