Invitrogen™ Folate Receptor alpha Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101588

Catalog No. PIPA5101588

Description

Antibody detects endogenous levels of total FOLR1.

The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.

Specifications

• Antigen: Folate Receptor alpha
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FOLR1
• Gene Alias: 66/67kDa; AA407891; adult folate-binding protein; eIF3 p66; EIF3D; eIF3d {ECO:0000255; eIF3p66; eIF3-p66; EIF3S7; eIF-3-zeta; eIF3-zeta; eIF-3-zeta {ECO:0000255; Eukaryotic translation initiation factor 3 subunit 7; eukaryotic translation initiation factor 3 subunit 7 {ECO:0000255; eukaryotic translation initiation factor 3 subunit D; eukaryotic translation initiation factor 3 subunit D {ECO:0000255; eukaryotic translation initiation factor 3, subunit 7 (zeta); eukaryotic translation initiation factor 3, subunit 7 zeta, 66/67kDa; eukaryotic translation initiation factor 3, subunit D; FBP; Fbp1; folate binding protein; folate binding protein 1; folate receptor 1; folate receptor 1 (adult); folate receptor alpha; Folate receptor, adult; folate-binding protein 1; Folbp1; Folbp-1; FOLR; FOLR1; FR-alpha; HAMAP-Rule:MF_03003}; KB cells FBP; MOv18; Ovarian tumor-associated antigen MOv18; translation initiation factor eIF3 p66; translation initiation factor eIF3 p66 subunit
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14275, 171049, 2348
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P15328, P35846
• Gene Symbols: FOLR1
• Immunogen: A synthesized peptide derived from human FOLR1(Accession P15328), corresponding to amino acid residues G48-R98.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov