FOLR2 Monoclonal Antibody (OTI5B1), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA808018

Catalog No. 50-168-1881

Description

FOLR2 is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients.

Specifications

• Antigen: FOLR2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P14207
• Gene Symbols: FOLR2
• Immunogen: Human recombit protein fragment corresponding to amino acids 20-221 of human FOLR2 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI5B1
• Conjugate: Unconjugated
• Gene: FOLR2
• Gene Alias: BETA-HFR, FBP, FBP/PL-1, FR-BETA, FR-P3
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2350
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid