FOLR2 Mouse anti-Human, Clone: OTI8G1, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF808017

Catalog No. 50-166-8602

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

FOLR2 is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients.

Specifications

• Antigen: FOLR2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: FOLR2
• Gene Alias: BETA-HFR, FBP, FBP/PL-1, FR-BETA, FR-P3
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2350
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI8G1
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P14207
• Gene Symbols: FOLR2
• Immunogen: Human recombit protein fragment corresponding to amino acids 20-221 of human FOLR2 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1