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Invitrogen™ FOLR4 Polyclonal Antibody
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Catalog No. PIPA547813
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100 μg
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Catalog No. Quantity
PIPA547813 100 μg
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Catalog No. PIPA547813 Supplier Invitrogen™ Supplier No. PA547813
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Description

Sheep Polyclonal Antibody

In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) FOLR1, rhFOLR2, rhFOLR3, and rhFOLR4 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

FR4 is a heavily glycosylated 35 kD receptor for folic acid and the physiologic circulating form of the vitamin, N5-methyltetrahydrofolate. Natural T regs have high levels of FR4 and together with CD25 can be used to distinguish natural Tregs, effector T cells, memory-like T cells and naive T cells. In vivo studies with eBioTH6 show a decrease in the number of CD4+CD25+ cells and an enhanced tumor response leading to the elimination of advanced stages of tumors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FOLR4
Applications Flow Cytometry, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene Izumo1r
Gene Accession No. Q9EQF4
Gene Alias 0910001L11Rik; C86255; Folate receptor 4; folate receptor 4 (delta); folate receptor 4 (delta) homolog; folate receptor 4, delta (putative); folate receptor delta; Folate-binding protein 3; Folbp3; Folr4; FR-delta; IZUMO1 receptor protein JUNO; IZUMO1 receptor, JUNO; Izumo1r; Juno; probable folate receptor delta; sperm-egg fusion protein Juno
Gene Symbols Izumo1r
Host Species Sheep
Immunogen E. coli-derived recombinant mouse FOLR4 Gly20-Ser100.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64931
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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