FOS Mouse anti-Human, Mouse, Clone: 1G2C5, Proteintech

Catalog No.	Quantity
50-173-7008	150 μL

Catalog No. 50-173-7008 Supplier Proteintech Group Inc Supplier No. 665901IG150UL

Description

Mouse Monoclonal Antibody

FBJ murine osteosarcoma viral oncogene homolog is commonly known as Cellular protooncogene Fos (c-Fos). It belongs to the fos transcription factor family and is encoded by the C-FOS gene located on chromosome 14. c-Fos heterodimerizes with c-Jun to form the Activator Protein -1 (AP-1) transcription factor which regulates transcription of several genes that play an important role in cellular signal transduction, cell proliferation and differentiation. c-Fos has been shown to be phosphorylated by various stimuli including growth factors and insulin at atleast seven different sites. The best known upstream kinase for phosphorylation at Threonine 232 is ERK MAPK which regulates localization of c-Fos to the nucleus and is thus important for c-Fos induced transcriptional activity.

Specifications

• Antigen: FOS
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 1G2C5
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: FOS
• Gene Accession No.: P01100, P01101
• Gene Alias: AP 1, C FOS, Cellular oncogene fos, FOS, G0S7, Proto oncogene c Fos
• Gene Symbols: FOS
• Host Species: Mouse
• Immunogen: FOS Fusion Protein Ag24340
• Purification Method: Protein G
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 14281, 2353
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1