Invitrogen™ FOXA2 Recombinant Rabbit Monoclonal Antibody (9H5L7)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ 701698

Catalog No. 70-169-8

Description

This antibody is predicted to react with Monkey, Horse, Cat and Dog. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

FOXA2 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin. They also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. FOXA2 has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified.

Specifications

• Antigen: FOXA2
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.2
• Gene Accession No.: Q9Y261
• Gene Symbols: FOXA2
• Immunogen: Protein corresponding to Human FOXA2 (aa 236-451).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ChIP Assay, Western Blot, Immunocytochemistry
• Clone: 9H5L7
• Conjugate: Unconjugated
• Gene: FOXA2
• Gene Alias: FKHL20; forkhead box A2; forkhead box protein A2; Foxa2; hepatic nuclear factor-3-beta; hepatocyte nuclear factor 3 beta (winged helix transcription factor); hepatocyte nuclear factor 3, beta; hepatocyte nuclear factor 3-beta; hepatocyte nuclear factor-3beta; HNF3B; Hnf-3b; HNF3beta; HNF-3BETA; HNF-3-beta; HNF3-beta; MGC19807; putative; RONU; TCF3B; TCF-3B; transcription factor; transcription factor 3B; transcription factor Foxa2; WHN
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3170
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

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