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Invitrogen™ FOXB1/FOXB2 Polyclonal Antibody
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Catalog No. PIPA575259
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100 μL
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PIPA575259 100 μL
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Catalog No. PIPA575259 Supplier Invitrogen™ Supplier No. PA575259
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are members of the FOX family and each contain one forkhead DNA-binding domain. Both FOXB1 and FOXB2 localize to the nucleus where they are thought to function as transcription factors that can bind to DNA via their forkhead domains. In mice, defects in the gene encoding FOXB1 are associated with retarded development of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FOXB1/FOXB2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene FOXB2
Gene Accession No. Q5VYV0, Q64732, Q64733, Q99853
Gene Alias bA159H20.4; C43; Fkh4; Fkh5; forkhead box B1; forkhead box B1a; forkhead box B1b; forkhead box B2; forkhead box protein B1; Forkhead box protein B2; forkhead homolog 4; Foxb1; Foxb1a; Foxb1b; FOXB2; Hfh-e5.1; HFKH-5; mesoderm/mesenchyme forkhead 3; Mf3; Transcription factor FKH-4; transcription factor FKH-5; Twh
Gene Symbols FOXB1, FOXB2
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 40-87 of Human FoxB1.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14240, 27023, 367106, 442425, 64290, 691398
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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