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Invitrogen™ FOXC1 Polyclonal Antibody
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Catalog No. PIPA518458
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100 μg
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Catalog No. Quantity
PIPA518458 100 μg
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Catalog No. PIPA518458 Supplier Invitrogen™ Supplier No. PA518458
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Description

Goat Polyclonal Antibody

This antibody is predicted to react with mouse and porcine based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

FOXC1 is a protein belonging to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this protein is not known, however, it plays a role in the regulation of FGF19-FGFR4-MAPK pathway to promote both the development and maintenance of anterior segment structures within the eye. Mutations in this gene cause various glaucoma, iridogoniodysgenesis anomaly, Peters anomaly that includes central corneal leukoma, absence of the posterior corneal stroma and Descemetmembrane and Axenfeld-Rieger anomaly characterized by posterior corneal embryotoxon, iris adhesion to the Schwalbe line, hypertelorism, hypoplasia of the malar bones, congenital absence of some teeth and mental retardation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FOXC1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene FOXC1
Gene Accession No. Q12948
Gene Alias ARA; ch; congenital hydrocephalus; Fkh1; fkh-1; Fkhl7; forkhead box C1; forkhead box C1 protein; forkhead box protein C1; forkhead, drosophila, homolog-like 7; forkhead/winged helix-like transcription factor 7; forkhead-related activator 3; forkhead-related protein FKHL7; Forkhead-related transcription factor 3; Foxc1; FREAC3; FREAC-3; frkhda; HGNC:3800; IGDA; IHG1; IRID1; Mesoderm/mesenchyme forkhead 1; Mf1; MF-1; Mf4; myeloid factor-delta; RIEG3; Transcription factor FKH-1
Gene Symbols FOXC1
Host Species Goat
Immunogen Synthetic peptide sequence (DAVKDKEEKDRLH) corresponding to the internal amino acids of FOXC1 (aa 178-191).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2296
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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