FOXO3 Monoclonal Antibody (OTI6H9), TrueMAB™, OriGene

Catalog No.	Quantity
50-168-2806	100 μL

Catalog No. 50-168-2806 Supplier OriGene Supplier No. TA809457

Description

Mouse Monoclonal Antibody

FOXO3 is a ubiquitously expressed 75 kDa protein member of a subfamily of the forkhead homeotic gene family of transcription factors and shuttles between the cytoplasm and nucleus. FOXO transcription factors are key players of cell fate decisions, metabolism, stress resistance, tumor suppression and are regulated by growth factors, oxidative stress or nutrient deprivation. FOXO3 is involved with mTOR in the regulation of autophagy in skeletal muscle, and activates protein degradation in atrophying muscle cells. FOXO3 has also been implicated in several neurodegenerative disorders including aging, neuromuscular disease, systemic lupus erythmatosus, stroke and diabetic complications.

Specifications

• Antigen: FOXO3
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI6H9
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: FOXO3
• Gene Accession No.: O43524
• Gene Alias: AF6q21, FKHRL1, FKHRL1P2, FOXO2, FOXO3A
• Gene Symbols: FOXO3
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 374-673 of human FOXO3 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2309
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1