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Invitrogen™ FOXP2 Monoclonal Antibody (CL5310)
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Catalog No. PIMA531418
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100 μL
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PIMA531418 100 μL
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Catalog No. PIMA531418 Supplier Invitrogen™ Supplier No. MA531418
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Description

Mouse Monoclonal Antibody

Immunogen sequence: AQQLVFQQQL LQMQQLQQQQ HLLSLQRQGL ISIPPGQAAL PVQSLPQAGL SPAEIQQLWK EVTGVHSMED NGIKHGGLDL TTNNSSSTTS SNTSKASPPI THHS Highest antigen sequence indentity to the following orthologs: Rat - 97%, Mouse - 99%.

FOXP2 is a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FOXP2
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Monoclonal
Clone CL5310
Concentration 0.7 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene FOXP2
Gene Accession No. O15409, P58463
Gene Alias 2810043D05Rik; AI449000; CAG repeat protein 44; CAG-16; CAGH44; D0Kist7; DKFZp686H1726; forkhead box P2; forkhead box protein P2; forkhead/winged-helix transcription factor; FOXP2; OTTHUMP00000196932; RGD1559697; SPCH1; TNRC10; trinucleotide repeat containing 10; trinucleotide repeat-containing gene 10 protein
Gene Symbols FOXP2
Host Species Mouse
Immunogen Recombinant protein fragment of Human FOXP2 (Product #RP-95090)
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114142, 93986
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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