Invitrogen™ FOXP2 Polyclonal Antibody

Catalog No.	Quantity
PIPA5143453	100 μL

Catalog No. PIPA5143453 Supplier Invitrogen™ Supplier No. PA5143453

Description

Rabbit Polyclonal Antibody

Store as concentrated solution. Centrifuge briefly prior to opening vial.

FOXP2 is a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.

Specifications

• Antigen: FOXP2
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 2.18 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 20% glycerol and 0.025% Proclin 300; pH 7
• Gene: FOXP2
• Gene Accession No.: O15409, P0CF24, P58463
• Gene Alias: 2810043D05Rik; AI449000; CAG repeat protein 44; CAG-16; CAGH44; D0Kist7; DKFZp686H1726; forkhead box P2; forkhead box protein P2; forkhead/winged-helix transcription factor; FOXP2; OTTHUMP00000196932; RGD1559697; SPCH1; TNRC10; trinucleotide repeat containing 10; trinucleotide repeat-containing gene 10 protein
• Gene Symbols: FOXP2
• Host Species: Rabbit
• Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human FOXP2. The exact sequence is proprietary.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 114142, 500037, 93986
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG