Invitrogen™ FOXR1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5113854

Catalog No. PIPA5113854

Description

Immunogen sequence: KKPNPDKDGP DYEPNLWMWV NPNIVYPPGK LEVSGRRKRE DLTSTLPSSQ For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%.

The forkhead-box (FOX) genes comprise a superfamily of at least 43 members that express proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOX family members are monomeric, helix-turn-helix proteins with a core DNA-binding domain of approximately 110 amino acids. FOX transcription factors play roles in determining cell fate during early development. FOXR1 (forkhead box protein R1), also known as FOXN5 (forkhead box protein N5) or DLNB13, is a 292 amino acid nuclear protein that belongs to the FOX family and contains one forkhead DNA-binding domain. Through chromosomal aberrations such as retroviral integration, gene amplification or translocation, FOXR1 may be involved the development of certain invasive carcinomas.

Specifications

• Antigen: FOXR1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Foxr1
• Gene Alias: DLNB13; Forkhead box protein N5; forkhead box protein R1; forkhead box R1; forkhead box R1 variant 1; forkhead box R1 variant 2; Foxn5; FOXR1; Gm1115
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 283150
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q6PIV2
• Gene Symbols: Foxr1
• Immunogen: Synthetic peptide directed towards the N terminal region of human FOXR1 (aa 38-87).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov