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Invitrogen™ FOXRED2 Polyclonal Antibody
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Catalog No. PIPA534345
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100 μg
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Catalog No. Quantity
PIPA534345 100 μg
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Catalog No. PIPA534345 Supplier Invitrogen™ Supplier No. PA534345
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Description

Rabbit Polyclonal Antibody

A suggested positive control is human lung tissue lysate. PA5-34345 can be used with blocking peptide PEP-1388.

FOXRED2, also known as ERFAD, is an endoplasmic reticulum (ER) luminal flavoprotein which may function in ER associated degradation (ERAD). It has been proposed to bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. Upon knockdown of FOXRED2, the degradation of the ERAD model substrate ribophorin 332 is delayed, and the overall level of polyubiquitinated cellular proteins is decreased. Defects in the related protein FOXRED1 are a cause of mitochondrial complex I deficiency (MT-C1D), suggesting the FOXRED2 may also play a role in MT-C1D.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FOXRED2
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene FOXRED2
Gene Accession No. Q8IWF2
Gene Alias Endoplasmic reticulum flavoprotein associated with degradation; ER flavoprotein associated with degradation; ERFAD; FAD dependent oxidoreductase domain containing 2; FAD-dependent oxidoreductase domain containing 2; FAD-dependent oxidoreductase domain-containing protein 2; FOXRED2
Gene Symbols FOXRED2
Host Species Rabbit
Immunogen A 17 amino acid synthetic peptide near the amino terminus of human FOXRED2.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80020
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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