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Invitrogen™ FPGT Polyclonal Antibody
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Catalog No. PIPA5119127
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200 μL
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PIPA5119127 200 μL
PIPA5121977 20 μL
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Catalog No. PIPA5119127 Supplier Invitrogen™ Supplier No. PA5119127
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Description

Rabbit Polyclonal Antibody

FPGT Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose; the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FPGT
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene FPGT
Gene Accession No. G5E8F4, O14772
Gene Alias 1700016E03Rik; Fpgt; fucose-1-phosphate guanyltransferase; fucose-1-phosphate guanylyltransferase; GDP-beta-L-fucose pyrophosphorylase; GDP-L-fucose diphosphorylase; GDP-L-fucose pyrophosphorylase; GFPP
Gene Symbols FPGT
Host Species Rabbit
Immunogen Recombinant protein Fucose-1-Phosphate Guanylyltransferase. The antigen corresponds to amino acid range 314-513 of the target protein.
Purification Method Antigen affinity chromatography, Protein A
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 75540, 8790
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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