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Invitrogen™ FPR1 Polyclonal Antibody
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Catalog No. PIPA533535
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50 μg
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PIPA533535 50 μg
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Catalog No. PIPA533535 Supplier Invitrogen™ Supplier No. PA533535
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human (100%) Chimpanzee, Gorilla (94%) Orangutan (88%) Gibbon (81%).

FPR1 is a member of chemoattractant/chemokine GPCRs expressed mainly on leukocytes, neutrophils and monocytes. FPR1 is a seven transmembrane pertussis toxin-sensitive GPCR and binds to formylated peptides generated by bacteria resulting in leukocyte trafficking to the site of inflammation. Ligand binding to FPR results in activation of multiple effectors including phospholipase C leading to calcium mobilization and PKC activation. Other implications of FPR signaling include polarization of actin cytoskeleton, activation of various integrins, increased cell migration, phagocytosis, degranulation and release of reactive oxygen intermediates.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FPR1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene FPR1
Gene Accession No. P21462
Gene Alias fMet-Leu-Phe receptor; fMLF-R; FMLP; fMLP receptor; formyl peptide receptor 1; FPR; Fpr receptor; FPR1; FPR-1; lipoxin A4 receptor; LXA4R; N-formyl peptide receptor; N-formylpeptide chemoattractant receptor
Gene Symbols FPR1
Host Species Rabbit
Immunogen Synthetic 16 amino acid peptide from 2nd extracellular domain of human FPR1.
Purification Method Antigen Affinity Chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2357
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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