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Tocris Bioscience™ FR 180204
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Catalog No. 370610R
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Catalog No. Quantity
37-061-0R 10 mg
37-065-0R 50 mg
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Catalog No. 37-061-0R Supplier Tocris Bioscience™ Supplier No. 3706/10
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Description

Selective ERK inhibitor

FR 180204 is a selective ERK inhibitor (IC50 values are 0.14 and 0.31 μM for ERK2 and ERK1 respectively). Displays 30-fold selectivity for ERK over p38α (IC50 = 10 μM); displays no activity against human recombinant MEK1, MKK4, IKKα, PKCα, Src, Syc and PDGFα at concentrations less than 30 μM. Also inhibits TGFβ-induced AP-1 activation in Mv1Lu cells (IC50 = 3.1 μM).

Specifications

Quantity 10 mg
Product Type FR 180204
Purity >98%
Molecular Weight (g/mol) 327.34
Inhibitors FR 180204

For Research Use Only

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