FREM1 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 130861AP150UL

Catalog No. 50-172-8478

Description

This antibody recognizes isoform 1 (244 kDa), isoform 2 (80 kDa) and isoform 3 (43 kDa).

FREM1 is a member of the FRAS1-related extracellular matrix protein family and is thought to play a role in craniofacial and renal development. FREM1 functions as an extracellular matrix protein that is essential for epidermal adhesion during embryogenesis and may also participate in epidermal differentiation. It is recognized by cells in the embryonic skin and hair follicles through different members of the integrin family. Deficiency in the Fras1/Frem genes gives rise to the bleb phenotype, which is equivalent to the human hereditary disorder Fraser syndrome.

Specifications

• Antigen: FREM1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FREM1
• Gene Alias: C9orf143, C9orf145, C9orf154, FREM1, Protein QBRICK, QBRICK, RP11 439N12.3
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 158326
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.13 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: Q5H8C1
• Gene Symbols: FREM1
• Immunogen: FREM1 Fusion Protein Ag3617
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG