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Invitrogen™ FREM2 Polyclonal Antibody
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Catalog No. PIPA5120413
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100 μL
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PIPA5120413 100 μL
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Catalog No. PIPA5120413 Supplier Invitrogen™ Supplier No. PA5120413
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Description

Rabbit Polyclonal Antibody

Positive test controls include: Jurkat, HepG2, 293T. The target is usually found in the following locations: Cell membrane, Extracellular side, Single-pass type I membrane protein. Immunogen sequence: QPAAFGRALL SPGLAGAAGV PAEEAIVLAN RGLRVPFGRE VWLDPLHDLV LQVQPGDRCA VSVLDNDALA QRPGRLSPKR FPCDFGPGEV RYSHLGARSP SRDRVRLQLR YDAPGGAVVL PLVLEVEVVF TQLEVVTRNL PLVVEELLGT SNALDARSLE FAFQPETEEC RVGILSGLGA LPRYGELLHY PQVPGGAREG GAPETLLMDC KAFQELGVRY RHTAASRSPN RDWIPMVVEL RSRGAPVGSP ALKR.

FREM2 is a member of the FRAS1-related extracellular matrix protein family and like FREM1, mutations in the FREM2 gene are associated with Fraser syndrome. FREM2 localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes and is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The FREM2 gene is one of several genes whose transcription is affecteded by TFAP2C, a transcription factor involved in mammary development, differentiation, and oncogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FREM2
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.43 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene FREM2
Gene Accession No. Q5SZK8, Q6NVD0
Gene Alias 6030440P17Rik; 8430406N05Rik; b2b1562Clo; ECM3 homolog; FRAS1 related extracellular matrix protein 2; FRAS1-related extracellular matrix protein 2; FREM2; Gm409; my; ne; NV domain containing protein NV1; NV domain-containing protein 1; Nv1
Gene Symbols FREM2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 47-300 of human FREM2 (NP_997244.4).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 242022, 341640
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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