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FREM2 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA555986
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100 μL
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PIPA555986 100 μL
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Catalog No. PIPA555986 Supplier Thermo Scientific Supplier No. PA555986

Description

Rabbit Polyclonal Antibody

Immunogen sequence: TFDGVREMRE AFTVHLKPDE NMIAEMQLTK AIVYIEEMSS MADVTFPSVP QIVSLLMYDD TSKAKESAEP MSGYPVICIT ACNPKYSDYD KTGSICASEN INDTLTRYRW LISAPAGPDG VTSPMR Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 84%.

FREM2 is a member of the FRAS1-related extracellular matrix protein family and like FREM1, mutations in the FREM2 gene are associated with Fraser syndrome. FREM2 localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes and is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The FREM2 gene is one of several genes whose transcription is affecteded by TFAP2C, a transcription factor involved in mammary development, differentiation, and oncogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FREM2
Applications Immunocytochemistry, Immunohistochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene FREM2
Gene Accession No. Q5SZK8
Gene Alias 6030440P17Rik; 8430406N05Rik; b2b1562Clo; ECM3 homolog; FRAS1 related extracellular matrix protein 2; FRAS1-related extracellular matrix protein 2; FREM2; Gm409; my; ne; NV domain containing protein NV1; NV domain-containing protein 1; Nv1
Gene Symbols FREM2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human FREM2
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 341640
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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