Invitrogen™ Frizzled-2 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518884

Catalog No. PIPA518884

Description

This antibody is predicted to react with mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.

This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways.

Specifications

• Antigen: Frizzled-2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Fzd2
• Gene Alias: AL033370; AW456835; Dfrizzled2; Drosophila polarity gene (frizzled) homologue; Drosophila polarity gene homolog 2; frizzled 2, seven transmembrane spanning receptor; frizzled class receptor 2; frizzled family receptor 2; frizzled homolog 2; frizzled homolog 2 (Drosophila); frizzled-10; Frizzled-2; Fz10; fz-10; Fz2; Fz-2; Fzd10; Fzd2; fzE2; hFz2; Mfz10; Mfz10a; mFz2; rFz2
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 2535
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q14332
• Gene Symbols: Fzd2
• Immunogen: Synthetic peptide sequence (RYATLEHPFHCPR) corresponding to the internal amino acids of FZD2 (aa 191-204).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG