Invitrogen™ FRS2 Recombinant Rabbit Monoclonal Antibody (HL1774)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA547176

Catalog No. PIMA547176

Description

Store as concentrated solution. Centrifuge briefly prior to opening vial.

Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1. [UniProt].

Specifications

• Antigen: FRS2
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: Q8C180, Q8WU20
• Gene Symbols: FRS2
• Immunogen: Recombinant fragment of human FRS2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: HL1774
• Conjugate: Unconjugated
• Gene: FRS2
• Gene Alias: 4732458E18; C330018A15Rik; FGFR signalling adaptor; FGFR substrate 2; FGFR-signaling adaptor SNT; fibroblast growth factor receptor substrate 2; FRS1A; FRS2; Frs2a; FRS2alpha; FRS2-alpha; SNT; SNT1; SNT-1; SNT2; suc1-associated neurotrophic factor target 1
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 10818, 314850, 327826
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid