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FRS2 Mouse anti-Human, Clone: 4E10H12, Proteintech
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Catalog No. 501736696 Shop All Proteintech Group Inc Products
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50-173-6696 150 μL
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Catalog No. 50-173-6696 Supplier Proteintech Group Inc Supplier No. 662631IG150UL
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Mouse Monoclonal Antibody

Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3- kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.

Specifications

Antigen FRS2
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 4E10H12
Concentration 1.49 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene FRS2
Gene Accession No. Q8WU20
Gene Alias FGFR signaling adaptor SNT, FGFR substrate 2, FRS2, FRS2A, FRS2alpha, SNT, SNT 1, SNT1
Gene Symbols FRS2
Host Species Mouse
Immunogen FRS2 Fusion Protein Ag19299
Purification Method Protein A
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10818
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG3
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