Invitrogen™ FTO Monoclonal Antibody (5-2H10)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA533105

Catalog No. PIMA533105

Description

FTO Monoclonal Antibody for ICC/IF, Western Blot

FTO is a novel protein and a member of the non-heme dioxygenase (Fe(II)-and 2-oxoglutarate-dependent dioxygenases) superfamily. Amino acid conservation patterns support this hypothesis and indicates that both 2-oxoglutarate and iron should be important for FTO function. Though not much is yet known about FTO, it is thought that the protein may somehow modify the activity of genes involved in metabolism and fat storage, which in turn may influence a person's risk of obesity.

Specifications

• Antigen: FTO
• Classification: Monoclonal
• Concentration: ~1.0 mg/mL
• Formulation: 10mM HEPES with 50% glycerol, 150mM NaCl, 100μg/mL BSA and no preservative; pH 7.5
• Gene Accession No.: Q2A121, Q8BGW1, Q9C0B1
• Gene Symbols: Fto
• Immunogen: Synthetic peptide corresponding to amino acid residues from the N-terminal region of rat FTO, conjugated to keyhole limpet hemocyanin (KLH).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Western Blot, Immunocytochemistry
• Clone: 5-2H10
• Conjugate: Unconjugated
• Gene: Fto
• Gene Alias: AlkB homolog 9; ALKBH9; alpha-ketoglutarate-dependent dioxygenase FTO; AW743446; BMIQ14; fat mass and obesity associated; fat mass and obesity-associated protein; fatso; FTO; GDFD; KIAA1752; m6A(m)-demethylase FTO; MGC5149; mKIAA1752; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; mRNA N(6)-methyladenosine demethylase FTO; Protein fatso; protein fto; RGD1305121; tRNA N1-methyl adenine demethylase FTO; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 26383, 291905, 79068
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid