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Invitrogen™ FTO Monoclonal Antibody (5-2H10)
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Catalog No. PIMA533105
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PIMA533105 100 μL
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Catalog No. PIMA533105 Supplier Invitrogen™ Supplier No. MA533105
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Description

Mouse Monoclonal Antibody

FTO Monoclonal Antibody for ICC/IF, Western Blot

FTO is a novel protein and a member of the non-heme dioxygenase (Fe(II)-and 2-oxoglutarate-dependent dioxygenases) superfamily. Amino acid conservation patterns support this hypothesis and indicates that both 2-oxoglutarate and iron should be important for FTO function. Though not much is yet known about FTO, it is thought that the protein may somehow modify the activity of genes involved in metabolism and fat storage, which in turn may influence a person's risk of obesity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FTO
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 5-2H10
Concentration ~1.0 mg/mL
Conjugate Unconjugated
Formulation 10mM HEPES with 50% glycerol, 150mM NaCl, 100μg/mL BSA and no preservative; pH 7.5
Gene Fto
Gene Accession No. Q2A121, Q8BGW1, Q9C0B1
Gene Alias AlkB homolog 9; ALKBH9; alpha-ketoglutarate-dependent dioxygenase FTO; AW743446; BMIQ14; fat mass and obesity associated; fat mass and obesity-associated protein; fatso; FTO; GDFD; KIAA1752; m6A(m)-demethylase FTO; MGC5149; mKIAA1752; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; mRNA N(6)-methyladenosine demethylase FTO; Protein fatso; protein fto; RGD1305121; tRNA N1-methyl adenine demethylase FTO; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO
Gene Symbols Fto
Host Species Mouse
Immunogen Synthetic peptide corresponding to amino acid residues from the N-terminal region of rat FTO, conjugated to keyhole limpet hemocyanin (KLH).
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26383, 291905, 79068
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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