FTO Mouse anti-Human, Clone: OTI4A1, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF809392

Catalog No. 50-166-9468

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Rising obesity rates are rapidly becoming a growing health concern in the developing world. The fat mass and obesity associated gene (FTO) is the first gene discovered to contribute to common forms of human obesity. FTO is a member of the non-heme dioxygenase superfamily, encoding a 2-oxoglutarate-dependent nucleic acid demethylase whose mRNA is widely expressed, especially in neurons of feeding-related nuclei of the brain. FTO mRNA in the arcuate nucleus in mice is up-regulated by feeding and down-regulated during fasting, although the opposite pattern has been observed in rats. At least four isoforms of FTO are known to exist.

Specifications

• Antigen: FTO
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: FTO
• Gene Alias: ALKBH9, BMIQ14, GDFD
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 79068
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI4A1
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q9C0B1
• Gene Symbols: FTO
• Immunogen: Full length human recombit protein of human FTO produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1