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FTO Mouse anti-Human, Clone: OTI4A1, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF809392

Encompass_Preferred

Catalog No. 50-166-9468


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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Rising obesity rates are rapidly becoming a growing health concern in the developing world. The fat mass and obesity associated gene (FTO) is the first gene discovered to contribute to common forms of human obesity. FTO is a member of the non-heme dioxygenase superfamily, encoding a 2-oxoglutarate-dependent nucleic acid demethylase whose mRNA is widely expressed, especially in neurons of feeding-related nuclei of the brain. FTO mRNA in the arcuate nucleus in mice is up-regulated by feeding and down-regulated during fasting, although the opposite pattern has been observed in rats. At least four isoforms of FTO are known to exist.
Specifications

Specifications

FTO
Monoclonal
Unconjugated
FTO
ALKBH9, BMIQ14, GDFD
Mouse
Affinity Chromatography
RUO
79068
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Immunohistochemistry (Paraffin), Western Blot
OTI4A1
PBS with 8% trehalose and no preservative; pH 7.3
Q9C0B1
FTO
Full length human recombit protein of human FTO produced in HEK293T cell.
100 μg
Primary
Human
Antibody
IgG1
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