FTO Mouse anti-Human, Clone: OTI4A1, liquid, TrueMAB™

Catalog No.	Quantity
50-168-2765	100 μL

Catalog No. 50-168-2765 Supplier OriGene Supplier No. TA809392

Description

Mouse Monoclonal Antibody

Rising obesity rates are rapidly becoming a growing health concern in the developing world. The fat mass and obesity associated gene (FTO) is the first gene discovered to contribute to common forms of human obesity. FTO is a member of the non-heme dioxygenase superfamily, encoding a 2-oxoglutarate-dependent nucleic acid demethylase whose mRNA is widely expressed, especially in neurons of feeding-related nuclei of the brain. FTO mRNA in the arcuate nucleus in mice is up-regulated by feeding and down-regulated during fasting, although the opposite pattern has been observed in rats. At least four isoforms of FTO are known to exist.

Specifications

• Antigen: FTO
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI4A1
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: FTO
• Gene Accession No.: Q9C0B1
• Gene Alias: ALKBH9, BMIQ14, GDFD
• Gene Symbols: FTO
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human FTO produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 79068
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1