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Invitrogen™ FTO Polyclonal Antibody
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Catalog No. PIPA5120656
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100 μL
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PIPA5120656 100 μL
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Catalog No. PIPA5120656 Supplier Invitrogen™ Supplier No. PA5120656
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Description

Rabbit Polyclonal Antibody

Positive test controls include: Mouse brain, Rat brain. Immunogen sequence: MKPRQRKQYF RNMKRSDDSE REKRRKRRRL LQELGEQRIP YLSPTDPGFQ DLWDSSYAGL ALRQSGTLPE GLHEKVQSAL LTLQRHGCLL RDLVRVRDRD VFTAVSRALV GQPGYTYRYL DTRLFTIPWH CEGEEGQKDE KGKPCCDSDL RDACKALWEL NQFFCSDVKQ QTNARGVKRT RSDTENSEDA PGEGMCEEES VKDRLVEEKT IEEEEEDSGQ GCSHSSPPSS TPPAAQASLV QFNVTLINYM NPAAMTQLKE EPYYGMGKMA VGWHHDENLV PLSPVAVYSY SCPAEPKNEG VTEKDGEGKS KEKEREAKGE GTSTEEVKKE GEASVKEDVE KEKTCWRVG.

FTO is a novel protein and a member of the non-heme dioxygenase (Fe(II)-and 2-oxoglutarate-dependent dioxygenases) superfamily. Amino acid conservation patterns support this hypothesis and indicates that both 2-oxoglutarate and iron should be important for FTO function. Though not much is yet known about FTO, it is thought that the protein may somehow modify the activity of genes involved in metabolism and fat storage, which in turn may influence a person's risk of obesity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FTO
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Fto
Gene Accession No. Q2A121, Q8BGW1, Q9C0B1
Gene Alias AlkB homolog 9; ALKBH9; alpha-ketoglutarate-dependent dioxygenase FTO; AW743446; BMIQ14; fat mass and obesity associated; fat mass and obesity-associated protein; fatso; FTO; GDFD; KIAA1752; m6A(m)-demethylase FTO; MGC5149; mKIAA1752; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; mRNA N(6)-methyladenosine demethylase FTO; Protein fatso; protein fto; RGD1305121; tRNA N1-methyl adenine demethylase FTO; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO
Gene Symbols Fto
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-349 of zebrafish FTO (XP_009301626.1).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26383, 291905, 79068
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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