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Invitrogen™ FTO Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120656

Catalog No. PIPA5120656


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Description

Description

Positive test controls include: Mouse brain, Rat brain. Immunogen sequence: MKPRQRKQYF RNMKRSDDSE REKRRKRRRL LQELGEQRIP YLSPTDPGFQ DLWDSSYAGL ALRQSGTLPE GLHEKVQSAL LTLQRHGCLL RDLVRVRDRD VFTAVSRALV GQPGYTYRYL DTRLFTIPWH CEGEEGQKDE KGKPCCDSDL RDACKALWEL NQFFCSDVKQ QTNARGVKRT RSDTENSEDA PGEGMCEEES VKDRLVEEKT IEEEEEDSGQ GCSHSSPPSS TPPAAQASLV QFNVTLINYM NPAAMTQLKE EPYYGMGKMA VGWHHDENLV PLSPVAVYSY SCPAEPKNEG VTEKDGEGKS KEKEREAKGE GTSTEEVKKE GEASVKEDVE KEKTCWRVG.

FTO is a novel protein and a member of the non-heme dioxygenase (Fe(II)-and 2-oxoglutarate-dependent dioxygenases) superfamily. Amino acid conservation patterns support this hypothesis and indicates that both 2-oxoglutarate and iron should be important for FTO function. Though not much is yet known about FTO, it is thought that the protein may somehow modify the activity of genes involved in metabolism and fat storage, which in turn may influence a person's risk of obesity.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

FTO
Polyclonal
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q2A121, Q8BGW1, Q9C0B1
Fto
Recombinant fusion protein containing a sequence corresponding to amino acids 1-349 of zebrafish FTO (XP_009301626.1).
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
ELISA, Western Blot
Unconjugated
Fto
AlkB homolog 9; ALKBH9; alpha-ketoglutarate-dependent dioxygenase FTO; AW743446; BMIQ14; fat mass and obesity associated; fat mass and obesity-associated protein; fatso; FTO; GDFD; KIAA1752; m6A(m)-demethylase FTO; MGC5149; mKIAA1752; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; mRNA N(6)-methyladenosine demethylase FTO; Protein fatso; protein fto; RGD1305121; tRNA N1-methyl adenine demethylase FTO; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO
Rabbit
Affinity Chromatography
RUO
26383, 291905, 79068
-20°C, Avoid Freeze/Thaw Cycles
Liquid
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