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Invitrogen™ FTO Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA146310

Catalog No. PA146310


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Description

Description

Suggested positive control: human brain lysate, human brain protein.

FTO is a novel protein and a member of the non-heme dioxygenase (Fe(II)-and 2-oxoglutarate-dependent dioxygenases) superfamily. Amino acid conservation patterns support this hypothesis and indicates that both 2-oxoglutarate and iron should be important for FTO function. Though not much is yet known about FTO, it is thought that the protein may somehow modify the activity of genes involved in metabolism and fat storage, which in turn may influence a person's risk of obesity.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

FTO
Polyclonal
Unconjugated
Fto
AlkB homolog 9; ALKBH9; alpha-ketoglutarate-dependent dioxygenase FTO; AW743446; BMIQ14; fat mass and obesity associated; fat mass and obesity-associated protein; fatso; FTO; GDFD; KIAA1752; m6A(m)-demethylase FTO; MGC5149; mKIAA1752; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; mRNA N(6)-methyladenosine demethylase FTO; Protein fatso; protein fto; RGD1305121; tRNA N1-methyl adenine demethylase FTO; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO
Rabbit
Antigen affinity chromatography
RUO
26383, 415718, 79068
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry, Western Blot
1.1 mg/mL
Tris citrate, Tris phosphate with 0.1% sodium azide; pH 7-8
Q8BGW1, Q9C0B1
Fto
Synthetic peptide corresponding to an C-terminal portion within residues 400-505 of the human protein. [Swiss-Prot# Q9C0B1].
100 μL
Primary
Human, Mouse, Monkey, Chicken
Antibody
IgG
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