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FTO Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA551074

Catalog No. PA551074


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Description

Description

FTO Polyclonal Antibody detects endogenous levels of FTO protein.

Rising obesity rates are rapidly becoming a growing health concern in the developing world. The fat mass and obesity associated gene (FTO) is the first gene discovered to contribute to common forms of human obesity. FTO is a member of the non-heme dioxygenase superfamily, encoding a 2-oxoglutarate-dependent nucleic acid demethylase whose mRNA is widely expressed, especially in neurons of feeding-related nuclei of the brain. FTO mRNA in the arcuate nucleus in mice is up-regulated by feeding and down-regulated during fasting, although the opposite pattern has been observed in rats. At least four isoforms of FTO are known to exist.
Specifications

Specifications

FTO
Polyclonal
Unconjugated
FTO
Liquid
FTO
Synthesized peptide derived from the N-terminal region of human FTO.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
ELISA, Western Blot
1 mg/mL
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Q9C0B1, Q8BGW1, Q2A121
KIAA1752
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
26383, 291905, 79068
Documents
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