FTO Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA551074
FTO Polyclonal Antibody detects endogenous levels of FTO protein.Rising obesity rates are rapidly becoming a growing health concern in the developing world. The fat mass and obesity associated gene (FTO) is the first gene discovered to contribute to common forms of human obesity. FTO is a member of the non-heme dioxygenase superfamily, encoding a 2-oxoglutarate-dependent nucleic acid demethylase whose mRNA is widely expressed, especially in neurons of feeding-related nuclei of the brain. FTO mRNA in the arcuate nucleus in mice is up-regulated by feeding and down-regulated during fasting, although the opposite pattern has been observed in rats. At least four isoforms of FTO are known to exist.
|Synthesized peptide derived from the N-terminal region of human FTO.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|ELISA, Western Blot|
|PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4|
|Q9C0B1, Q8BGW1, Q2A121|
|-20° C, Avoid Freeze/Thaw Cycles|
|26383, 291905, 79068|
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