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Invitrogen™ FTO Recombinant Superclonal™ Antibody (2HCLC)

Catalog No. 712913
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Catalog No. Quantity
71-291-3 100 μg
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Catalog No. 71-291-3 Supplier Invitrogen™ Supplier No. 712913
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Description

Rabbit Recombinant Superclonal Antibody

This antibody is predicted to react with Mouse, Rat, Bovine, Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit Superclonal™ antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Note: Formerly called Recombinant polyclonal antibody, this product is now rebranded as Recombinant Superclonal™ antibody. The physical product and the performance remain unchanged.

FTO is a novel protein and a member of the non-heme dioxygenase (Fe(II)-and 2-oxoglutarate-dependent dioxygenases) superfamily. Amino acid conservation patterns support this hypothesis and indicates that both 2-oxoglutarate and iron should be important for FTO function. Though not much is yet known about FTO, it is thought that the protein may somehow modify the activity of genes involved in metabolism and fat storage, which in turn may influence a person's risk of obesity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FTO
Applications Western Blot, RNA Immunoprecipitation, Immunocytochemistry
Classification Recombinant Superclonal
Clone 2HCLC
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene Fto
Gene Accession No. Q9C0B1
Gene Alias AlkB homolog 9; ALKBH9; alpha-ketoglutarate-dependent dioxygenase FTO; AW743446; BMIQ14; fat mass and obesity associated; fat mass and obesity-associated protein; fatso; FTO; GDFD; KIAA1752; m6A(m)-demethylase FTO; MGC5149; mKIAA1752; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; mRNA N(6)-methyladenosine demethylase FTO; Protein fatso; protein fto; RGD1305121; tRNA N1-methyl adenine demethylase FTO; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO
Gene Symbols Fto
Host Species Rabbit
Immunogen Protein corresponding to human FTO [aa1-aa188].
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79068
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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