Invitrogen™ FTO Recombinant Rabbit Monoclonal Antibody (4A5T6)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA551209

Catalog No. FEMA551209

Description

Immunogen sequence: STGTLDYILQ RCQLALQNVC DDVDNDDVSL KSFEPAVLKQ GEEIHNEVEF EWLRQFWFQG NRYRKCTDWW CQPMAQLEAL WKKMEGVTNA VLHEVKREGL PVEQRNEILT AILASLTARQ NLRREWHARC QSRIARTLPA DQKPECRPYW EKDDASMPLP FDLTDIVSEL RGQLLEAK.

FTO is a novel protein and a member of the non-heme dioxygenase (Fe(II)-and 2-oxoglutarate-dependent dioxygenases) superfamily. Amino acid conservation patterns support this hypothesis and indicates that both 2-oxoglutarate and iron should be important for FTO function. Though not much is yet known about FTO, it is thought that the protein may somehow modify the activity of genes involved in metabolism and fat storage, which in turn may influence a person's risk of obesity.

Specifications

• Antigen: FTO
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: Q2A121, Q8BGW1, Q9C0B1
• Gene Symbols: Fto
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 327-504 of human FTO (NP_001073901.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Format: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 4A5T6
• Conjugate: Unconjugated
• Gene: Fto
• Gene Alias: AlkB homolog 9; ALKBH9; alpha-ketoglutarate-dependent dioxygenase FTO; AW743446; BMIQ14; fat mass and obesity associated; fat mass and obesity-associated protein; fatso; FTO; GDFD; KIAA1752; m6A(m)-demethylase FTO; MGC5149; mKIAA1752; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; mRNA N(6)-methyladenosine demethylase FTO; Protein fatso; protein fto; RGD1305121; tRNA N1-methyl adenine demethylase FTO; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26383, 291905, 79068
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid
• Isotype: IgG