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  6. Fucosyltransferase 3/FUT3 Antibody (SPM194) - Azide and BSA Free, Novus Biologicals™

Fucosyltransferase 3/FUT3 Antibody (SPM194) - Azide and BSA Free, Novus Biologicals™
SDP

Catalog No. NBP247928B Shop All R&D Systems Products
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NBP247928B 0.2 mg
NBP247928A 0.1 mg
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Catalog No. NBP247928B Supplier Novus Biologicals Supplier No. NBP2479280.2MG

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.

Description

Mouse Monoclonal Antibody

Blood Group Lewis b Monoclonal antibody specifically detects Antigen in Guinea Pig, Human samples. It is validated for Immunofluorescence, Immunohistochemistry (Paraffin).

Specifications

Antigen Blood Group Lewis b
Applications Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone SPM194
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml
Formulation PBS with No Preservative
Gene Alias alpha-(1,3/1,4)-fucosyltransferase, Blood group Lewis alpha-4-fucosyltransferase, CD174, EC 2.4.1, EC 2.4.1.65, FT3B, Fucosyltransferase 3, fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group), Fucosyltransferase III, FucT-III, galactoside 3(4)-L-fucosyltransferase, LEfucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood groupincluded), Les, Lewis FT, MGC131739
Gene Symbols FUT3
Host Species Mouse
Immunogen Mucin isolated from a human ovarian cyst fluid
Molecular Weight of Antigen 45 kDa
Purification Method Protein A or G purified
Quantity 0.2 mg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2525
Test Specificity The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Lewis blood group antigens are carbohydrate moieties structurally integrated in mucous secretions. Lewis antigen system alterations have been described in gastric carcinoma and associated lesions. Anomalous expression of Lewis B antigen has been found in some non-secretory gastric carcinomas and colorectal cancers.
Target Species Human, Guinea Pig
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG1 κ
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